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Leonardo da Vinci, Landscape drawing for Santa Maria della Neve on 5th August 1473, 1473. Via Wikimedia Commons.
Leonardo was born left-handed, but was taught to write with his right hand from a very young age. [...] By looking at his writings, including from this drawing, one can see his right-handed calligraphy is educated and well done.
The new analysis [...] found “left-handed charcoal marks pretty much everywhere,” according to Deldicque, suggesting the famously left-handed Leonardo was involved in the drawing’s execution, though other parts of it were likely done by a right-handed apprentice.